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Article first published 2002,
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In-Focus Brief on Mercury Poisoning and Heavy Metal Toxicity

Mercury toxicity: risk, symptoms, and how to check if you are affected by mercury poisoning.

Toxicity caused by excessive mercury exposure is now becoming recognized as a widespread environmental problem and is continuing to attract a great deal of public attention.

A National Academy of Sciences study published in July, 2001 estimates that up to 60,000 children born in the USA each year may be affected by mercury toxicity, and in March, 2002 an environmental group had charged the FDA of failing to warn the public of the dangers of mercury contamination from eating tuna,which contain high levels of mercury.

The dangers of mercury toxicity, as with other heavy metals, has been known for some time, but it is only in recent years that the extent of the problem, and the sources of the health risk associated with these toxicities, especially mercury toxicity have become apparent. It has become so prevalent that it could be seen as a major public health concern.

In this brief you will learn about:
  • Mercury toxicity as a major public health concern
  • Main sources of mercury poisoning and heavy metal toxicity
  • Symptoms of mercury poisoning
  • How to test for mercury toxicity and other heavy metal toxicity

Heavy metal toxicity or poisoning arises when the body accumulates an excessive amount of a heavy metal, such as mercury, lead, arsenic, cadmium, aluminium or nickel which places the individual at risk for serious illness.

These heavy metals play no known biological role in the human body, unlike with some elements such as selenium, which is an effective antioxidant, iron, which is required by blood cells, and copper, which is an integral part of many enzymes. Since they are not useful to the organism, and because the body has storage sites for them, these heavy metals can accumulate in tissues over time and cause serious health problems.

Toxicity from mercury, in common with the other heavy metals, arises from environmental contamination and also from some unexpected sources as we shall see below. With mercury, it is the nature of the environmental sources that are particularly worrying in the context of nutrition.


Main Sources of mercury toxicity/poisoning:

  • Drinking contaminated water
  • Eating fish contaminated with mercury
  • Leaching of mercury from badly fitting dental fillings.
  • From vaccinations containing thimerosal.
Heavy metal toxicity from drinking contaminated water:
It has been estimated that the ordinary American is exposed to tap water containing heavy metals at levels exceeding the safe upper limit.

With lead, for example, it is estimated that 40 million Americans drink water containing levels exceeding the safe limit set by the EPA. The lead contamination comes mainly from lead plumbing in older homes and soldered joints in copper pipes.

Other heavy metal found in tap water include copper and arsenic. Copper serves as a co-factor for many enzymes and is required in the diet in small amounts for normal health. However, high doses of copper is dangerous to health. A single dose of 15 mg copper can cause nausea, vomiting, diarrhea and abdominal pain. More severe toxicity can cause liver and kidney damage.

The copper in tap water comes from corrosion of copper pipes and can accumulate overnight. In this case flushing the tap before using the water is highly recommended.

Arsenic has been found in tap water in levels substantially exceeding the EPA safe limit in several areas of the country. For example, earlier this year a US Department of Health investigation found high levels of arsenic in tap water samples in Churchill County, Nevada, and In Iowa, several public water supplies were found in mid 2001 to have high arsenic levels. Because of the risks of cancer from arsenic levels below the current limit of 50 parts per billion, the EPA has set new standards of 10 ppb to take effect in 2006.

Mercury from environmental contamination (derived mainly from coal-fired power plants and medical and municipal incinerators) eventually enter our water system through soil, rivers, streams and lakes. The form of mercury hazardous in drinking water is the inorganic form, which can easily be converted to the organic form, methylmercury, by bacterial action present in soil and water environments. As discussed below this is the form that eventually enters our food chain.

The maximum level of mercury in drinking water permitted by the EPA is 2 parts per billion. Although levels of mercury in tap water are generally within this limit, there have been reports of mercury exceeding the EPA safe limit in several areas of the country, most notably from well sources. In New Jersey, for example, a survey found 265 out of 2,239 wells with high mercury levels.

Toxicity from eating contaminated fish:
This is one of the main sources of mercury poisoning and one which is attracting a great deal of recent attention.

The FDA is coming under increasing pressure from environmental groups to warn the public of the dangers of eating tuna because it contains enough mercury to damage a developing foetus.
At least three states, Washington, New Jersey and Minnesota, have recommended pregnant women to limit tuna consumption to 1 1/2 cans per week, and in Canada and advisory was issued warning women of childbearing age and children to limit consumption of shark, swordfish and fresh tuna to one meal per month.

The FDA is coming under increasing pressure from environmental groups to warn the public of the dangers of eating tuna because it contains enough mercury to damage a developing foetus. At least three states, Washington, New Jersey and Minnesota, have recommended pregnant women to limit tuna consumption to 1 1/2 cans per week, and in Canada and advisory was issued warning women of childbearing age and children to limit consumption of shark, swordfish and fresh tuna to one meal per month.

The FDA since 2001 had already advised pregnant women, women who may become pregnant, and small children to avoid eating four types of fish: shark, swordfish, king mackerel and tilefish. However, tuna was not on the list of fish to avoid and the FDA recommendations that up to 12 ounces or 2 1/2 cans of tuna per week is safe to eat is being challenged by the environment working group.

It is important to note that not all fish are considered risky in the context of mercury contamination. Fish is high in omega-3 polyunsaturated fatty acids which is known to be beneficial to cardiovascular health. Therefore, rather than avoid all fish, it is more prudent to find good substitutes for the risky fish. There are many types of fish available and farm raised fish is one option. Only trace amounts of mercury, 40-100 times below the safe limit were found in common commercially produced fish.


Mercury Toxicity from dental fillings: Dental amalgams, or "silver fillings" contains about 50% mercury along with silver, tin, copper and zinc. Mercury tends to leach from the amalgam with release of mercury vapour so over time there is a real risk of a toxic load to the body posing a real health risk. Toxicity from dental amalgams has been the subject of debate for many years. The simple fact alone that mercury is highly toxic to the human body and that mercury release from amalgam readily occurs ( some studies show 10 micrograms per day released per amalgam) should sound an alarm.

Yet, despite the dangers that exist from the use of a highly toxic material in dental fillings, the fact remains that an estimated 92 % of US dentists use mercury amalgams.

In April, 2003 a Swedish evaluation of the use of mercury in dental practice effectively concluded that amalgam posed unacceptable risk. The expert in charge of the evaluation was quoted as saying that "amalgam as soon as possible should be banned in the whole of the European Union".

In the US, a bill was introduced in 2002 to ban mercury use in dental amalgam from the year 2006..


Mercury Toxicity from vaccinations containing thimerosal:
This is one of the most topical issues on mercury toxicity. It is one that is steadily gaining public awareness ever since the link between autism and vaccinations was first proposed. A little known fact before public awareness campaigns started is the fact that the preservative, thimerosal usually added to vaccines contain mercury. In 1999, the Centers for Disease Control and prevention (CDC) called for the removal of mercury from vaccines. Paradoxically, the CDC still continues to recommend the measles, mumps and rubella vaccine. Thimerosal structurevaccine containing thimerosal, gbgm-umc.org

Young children are particularly sensitive to mercury toxicity and statistics have shown that since the introduction of thimerosal in vaccines in 1990 there has been a 10-fold increase in the incidence of autism. Many parents also report the onset of autistic behavior in their children within days of a vaccination. Strikingly, 40 % of parents of autistic children are said to believe that vaccines cause the disease.

The effects of mercury on the central nervous system is well documented. Excessive prenatal exposure leads to delayed developmental functions including delayed walking, delayed speech development and hearing impairment.

The level of mercury exposure in vaccines has been put at 125-times the safe recommended limit by the Environmental Agency. A recent study also reports a strong correlation between the relative risk of autism and heart arrests and the dose of mercury contained in childhood vaccines. In contrast to such evidence, The Institute of Medicine has recently found no association between measles, mumps and rubella vaccine and autism.


How to tell if you are affected by mercury toxicity

Symptoms of mercury poisoning / toxicity

Mercury toxicity, as with other heavy metal toxicity, presents with various symptoms depending on the severity or level of the toxic exposure.

The body accumulates ingested amounts in the kidney, brain, liver and other body tissues including hair.

Symptoms of acute high-dose exposure Chronic exposure symptoms
These include:
abdominal pain, gastroenteritis, nausea, excessive salivation, poor coordination, loss of appetite and weight loss, anuria (urine production stops), and nephritis (kidney disease).
Generally affects the central nervous system. Symptoms include tremor, depression, memory loss, irritability, abnormal reflex, lethargy. Other symptoms are muscle weakness, inflammation of the gums, and immune system dysfunction and renal damage.

Long-term toxic exposure can also lead to infertility in men and women. Toxicity also affects pregnancy outcome and has also been linked with cardiovascular disease. In a study of over 2000 men, high hair mercury content was linked with an increased risk for heart disease and stroke.

In the young, mercury toxicity usually leads to childhood learning disability (see above discussion on autism).

However, bear in mind that none of the above symptoms is unique to mercury toxicity and may arise by other causes. Therefore, the only way to tell if you have accumulated a toxic amount of mercury is not by symptomatology alone, but by having a mercury test done.

Tests for mercury toxicity and other heavy metal toxicity/poisoning:

Of the tests available, the hair test, referred to as hair mineral analysis, is by far the easiest and most powerful diagnostic test for heavy metal toxicity that you can have done.

The hair mineral analysis is used by many health professionals, including many in the alternative medicine field, to check for mineral imbalances and deficiencies as well as for mercury poisoning and heavy metal toxicity. It has received much attention in this regard, and there are some limitations of the analysis largely with variations in results between labs, but overall it offers an accurate and convenient method to check for the presence of heavy metal toxicity.

The remarkable thing about the hair analysis is the convenience and ability to give information not only on mercury, but on all the other heavy metals as well. So, if you have any other heavy metal toxicity, such as lead toxicity, cadmium toxicity, arsenic toxicity, aluminium toxicity, barium toxicity or nickel toxicity, you will discover this with the test.

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Hair is used to determine mercury toxicity because hair accumulates heavy metals (as well as essential minerals) in concentrations 1000-times more than other biological tissue. Numerous scientific studies attest to the usefulness of hair analysis as a test for heavy metal toxicity. One doctor, who testified before the committee on Government reform on the association between mercury toxicity and autism, routinely uses hair analysis in her family practice which treats hundreds of autistic cases every year.

The other types of tests used for checking for mercury toxicity differ in the source of the biological sample used for testing: blood, urine or saliva. Each has its limitations.

The saliva test is performed when there is a suspect mercury poisoning or toxicity from mercury leaching from dental fillings. To perform the test, the person is asked to chew a special gum and collect their saliva before chewing and after chewing the gum. Both samples are then analyzed and if there is a marked difference between the before and after samples then this indicates that mercury leaching has occurred.

Bear in mind that this test does not tell you if you have mercury toxicity. This is because saliva is not considered a marker of body status for mercury. The main use is to tell if you are being exposed to mercury leaching from dental fillings that may be causing toxicity. Further tests to confirm mercury toxicity can then performed.

Blood and urine, unlike with hair analysis, give information on transient levels of mercury only. Urine testing is usually done as confirmatory tests to get detailed information on excretion and transport of mercury and the other heavy metals. Blood levels are influenced by the body homeostatic mechanism which attempts to keep levels within a narrow range. Blood level reflect recent exposure and is independent of tissue deposition.
For more information see our Bioanalysis Center if you wish to have a test done.



Useful references:
American Heart Association Asia Pacific Forum 24th April 2002.
Health Canada. Riedel D, Tremblay N, Tompkins E. (Eds.) State of Knowledge Report for Environmental Contaminants and Human Health in the Great Lakes Basin, Ottawa: 1997; p. 147.

http://www.atsdr.cdc.gov/NEWS/fallonei.html







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